The Big Bang Theory A woman who moves into an apartment across the hall from two brilliant but socially awkward physicists shows them how little they know about life outside of the laboratory.
How I Met Your Mother A father recounts to his children - through a series of flashbacks - the journey he and his four best friends took leading up to him meeting their mother.
Two and a Half Men A hedonistic jingle writer's free-wheeling life comes to an abrupt halt when his brother and 10-year-old nephew move into his beach-front house.
Suits On the run from a drug deal gone bad, brilliant college dropout Mike Ross finds himself working with Harvey Specter, one of New York City's best lawyers.
Modern Family Three different but related families face trials and tribulations in their own uniquely comedic ways.
Bones Forensic anthropologist Dr. Temperance "Bones" Brennan and cocky F.B.I. Special Agent Seeley Booth build a team to investigate murders. Quite often, there isn't more to examine than rotten flesh or mere bones.
90210 A Kansas family relocates to Beverly Hills, where their two children adapt to the infamous social drama of West Beverly Hills High.
Desperate Housewives Secrets and truths unfold through the lives of female friends in one suburban neighborhood, after the mysterious suicide of a neighbor.
Chuck When a computer geek inadvertently downloads critical government secrets into his brain, both the CIA and the NSA assign an agent to protect him and exploit his newfound skills.
Glee A group of ambitious misfits try to escape the harsh realities of high school by joining a glee club headed by a passionate Spanish teacher.
American Dad The random escapades of Stan Smith, a conservative C.I.A. Agent dealing with family life, and keeping America safe, all in the most absurd way possible.
Castle After a serial killer imitates the plots of his novels, successful mystery novelist Richard "Rick" Castle receives permission from the Mayor of New York City to tag along with an NYPD homicide investigation team for research purpo...
White Collar A white-collar criminal agrees to help the FBI catch other white-collar criminals using his expertise as an art and securities thief, counterfeiter, and conman.
New Girl After a bad break-up, Jess, an offbeat young woman, moves into an apartment loft with three single men. Although they find her behavior very unusual, the men support her - most of the time.
Californication A writer tries to juggle his career, his relationship with his daughter and his ex-girlfriend, as well as his appetite for beautiful women.
The Office A mockumentary on a group of typical office workers, where the workday consists of ego clashes, inappropriate behavior, and tedium.
SpongeBob SquarePants The misadventures of a talking sea sponge who works at a fast food restaurant, attends a boating school, and lives in an underwater pineapple.
The Fresh Prince of Bel-Air A streetwise, poor young man from Philadelphia is sent by his mother to live with his aunt, uncle and cousins in their Bel-Air mansion.
The Middle The daily mishaps of a married woman and her semi-dysfunctional family and their attempts to survive life in general in the town of Orson, Indiana.
Private Practice A spin-off of the medical drama "Grey's Anatomy" centering on the life of neonatal surgeon Addison Montgomery.